Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators | Journal of the American Chemical Society
Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions | Scientific Reports
A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects | Journal of Medicinal Chemistry
Majumdar Lab - Research Projects
Frontiers | Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder
Mitragynine - Wikipedia
Recreational Drug Kratom Hits the Same Brain Receptors as Strong Opioids - Scientific American
7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects | ACS Central Science
Evaluating kratom alkaloids using PHASE | PLOS ONE
Influence of G protein-biased agonists of μ-opioid receptor on addiction-related behaviors | SpringerLink
The effects of kratom on restraint–stress-induced analgesia and its mechanisms of action - ScienceDirect
Medicines | Free Full-Text | Mitragyna speciosa: Clinical, Toxicological Aspects and Analysis in Biological and Non-Biological Samples
Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions | Scientific Reports
Frontiers | Kratom Use Within the Context of the Evolving Opioid Crisis and the COVID-19 Pandemic in the United States
Pharmacological characterization of kratom derivatives at the µ, δ, and... | Download Scientific Diagram
Kappa Opioid Receptor Structure Revealed, A Potential Milestone in Medication Development | National Institute on Drug Abuse (NIDA)
Kratom Alkaloids as Probes for Opioid Receptor Function: Pharmacological Characterization of Minor Indole and Oxindole Alkaloids from Kratom | ACS Chemical Neuroscience
An updated assessment of the translational promise of G-protein-biased kappa opioid receptor agonists to treat pain and other indications without debilitating adverse effects - ScienceDirect
Scientists Just Solved a Major Piece of the Opioid Puzzle | WIRED
Neurobiology of Kratom and its main alkaloid mitragynine
Pharmaceutics | Free Full-Text | Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants
The science behind kratom's strange leaves
G protein‐biased kratom‐alkaloids and synthetic carfentanil‐amide opioids as potential treatments for alcohol use disorder - Gutridge - 2020 - British Journal of Pharmacology - Wiley Online Library
Opioid receptors: drivers to addiction? | Nature Reviews Neuroscience
